c-Kit-IN-3 is a potent and selective c-KIT kinase inhibitor. c-Kit-IN-3 displays great potencies against most of the gain-of function mutations in the juxtamembrane domain, drugresistant mutations in the ATP binding pocket, and activation loops.
MedKoo Cat#: 462480
Name: c-Kit-IN-3
CAS#: 2363169-01-9
Chemical Formula: C26H20ClF3N2O4
Exact Mass: 516.1064
Molecular Weight: 516.90
Elemental Analysis: C, 60.42; H, 3.90; Cl, 6.86; F, 11.03; N, 5.42; O, 12.38
The following data is based on the product molecular weight 516.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
