MedKoo Cat#: 462476 | Name: BMS-978587
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.

Chemical Structure

BMS-978587
CAS#1629125-65-0

Theoretical Analysis

MedKoo Cat#: 462476

Name: BMS-978587

CAS#: 1629125-65-0

Chemical Formula: C26H35N3O3

Exact Mass: 437.2678

Molecular Weight: 437.58

Elemental Analysis: C, 71.37; H, 8.06; N, 9.60; O, 10.97

Price and Availability

Size Price Availability Quantity
2mg USD 400.00 2 Weeks
5mg USD 750.00 2 Weeks
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Related CAS #
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Synonym
IDO-IN-4; IDO IN 4; IDO IN-4; IDO-IN 4; BMS-978587; BMS978587; BMS 978587
IUPAC/Chemical Name
(1R,2S)-2-(4-(diisobutylamino)-3-(3-(p-tolyl)ureido)phenyl)cyclopropane-1-carboxylic acid
InChi Key
VZYCPKLOYXSKAB-FGZHOGPDSA-N
InChi Code
InChI=1S/C26H35N3O3/c1-16(2)14-29(15-17(3)4)24-11-8-19(21-13-22(21)25(30)31)12-23(24)28-26(32)27-20-9-6-18(5)7-10-20/h6-12,16-17,21-22H,13-15H2,1-5H3,(H,30,31)(H2,27,28,32)/t21-,22-/m1/s1
SMILES Code
O=C(NC1=CC=C(C)C=C1)NC2=CC([C@@H](C3)[C@@H]3C(O)=O)=CC=C2N(CC(C)C)CC(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 437.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Balog, et al. Preparation of cycloalkylaryl amide compounds as indoleamine 2,3-dioxygenase and therapeutic uses thereof. From PCT Int. Appl. (2014), WO 2014150677 A1 20140925.