MedKoo Cat#: 462442 | Name: Topilutamide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Topilutamide is a topical nonsteroidal antiandrogen (NSAA).

Chemical Structure

Topilutamide
CAS#260980-89-0

Theoretical Analysis

MedKoo Cat#: 462442

Name: Topilutamide

CAS#: 260980-89-0

Chemical Formula: C13H11F6N3O5

Exact Mass: 403.0603

Molecular Weight: 403.24

Elemental Analysis: C, 38.72; H, 2.75; F, 28.27; N, 10.42; O, 19.84

Price and Availability

Size Price Availability Quantity
5mg USD 500.00 2 Weeks
10mg USD 750.00 2 Weeks
50mg USD 1,500.00 2 Weeks
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Related CAS #
No Data
Synonym
Topilutamide; BP766; BP 766; BP-766; Fluridil
IUPAC/Chemical Name
2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-3-(2,2,2-trifluoroacetamido)propanamide
InChi Key
YCNCRLKXSLARFT-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H11F6N3O5/c1-11(25,5-20-10(24)13(17,18)19)9(23)21-6-2-3-8(22(26)27)7(4-6)12(14,15)16/h2-4,25H,5H2,1H3,(H,20,24)(H,21,23)
SMILES Code
O=C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)C(C)(O)CNC(C(F)(F)F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 403.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Suresh PS, Srinivas NR, Mullangi R. Review of HPLC and LC-MS/MS assays for the determination of various nonsteroidal anti-androgens used in the treatment of prostate cancer. Biomed Chromatogr. 2018;32(1):10.1002/bmc.4034. doi:10.1002/bmc.4034