Vancomycin monohydrochloride is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding D-Ala-D-Ala peptidoglycan precursors, blocking cross-linking. It exhibits potent bioactivity against Gram-positive bacteria, including MRSA and Clostridioides difficile. The monohydrochloride salt enhances solubility and stability for intravenous formulations, ensuring effective systemic delivery.
MedKoo Cat#: 574494
Name: Vancomycin monohydrochloride
CAS#: 197638-25-8
Chemical Formula: C66H76Cl3N9O24
Exact Mass: 1483.4069
Molecular Weight: 1485.72
Elemental Analysis: C, 53.36; H, 5.16; Cl, 7.16; N, 8.48; O, 25.84
The following data is based on the product molecular weight 1,485.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
