CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibiting mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells.
MedKoo Cat#: 462390
Name: CCI-006
CAS#: 292053-42-0
Chemical Formula: C15H12N2O5S
Exact Mass: 0.0000
Molecular Weight: 332.33
Elemental Analysis: C, 54.21; H, 3.64; N, 8.43; O, 24.07; S, 9.65
The following data is based on the product molecular weight 332.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
