FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.
MedKoo Cat#: 462385
Name: FM26
CAS#: 2407981-35-3
Chemical Formula: 461.0754
Exact Mass: 461.0754
Molecular Weight: 461.83
Elemental Analysis: C, 57.22; H, 3.27; Cl, 7.68; F, 12.34; N, 9.10; O, 10.39
The following data is based on the product molecular weight 461.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
