MedKoo Cat#: 535018 | Name: MG 18553

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MG 18553 is a bioactive chemical.

Chemical Structure

MG 18553
MG 18553
CAS#72781-92-1

Theoretical Analysis

MedKoo Cat#: 535018

Name: MG 18553

CAS#: 72781-92-1

Chemical Formula: C11H18N2O7

Exact Mass: 290.1114

Molecular Weight: 290.27

Elemental Analysis: C, 45.52; H, 6.25; N, 9.65; O, 38.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MG 18553; MG-18553; MG18553
IUPAC/Chemical Name
Glutamic acid, N-((2-oxo-1-pyrrolidinyl)acetyl)-, monohydrate
InChi Key
OTUSBCWNXWHYRA-FJXQXJEOSA-N
InChi Code
InChI=1S/C11H16N2O6.H2O/c14-8(6-13-5-1-2-9(13)15)12-7(11(18)19)3-4-10(16)17;/h7H,1-6H2,(H,12,14)(H,16,17)(H,18,19);1H2/t7-;/m0./s1
SMILES Code
O=C(O)CC[C@@H](C(O)=O)NC(CN1C(CCC1)=O)=O.[H]O[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Amery W, Duyck F, Polak J, van den Bouwhuysen G. A multicentre double-blind study in acute diarrhoea comparing loperamide (R 18553) with two common antidiarrhoeal agents and a placebo. Curr Ther Res Clin Exp. 1975 Mar;17(3):263-70. PMID: 123844. 2: Gallino F, Di Valentin C, Pacchioni G. Band gap engineering of bulk ZrO2 by Ti doping. Phys Chem Chem Phys. 2011 Oct 21;13(39):17667-75. doi: 10.1039/c1cp21987a. Epub 2011 Sep 7. PMID: 21897973. 3: Thakur NS, Mandal N, Banerjee UC. Esterase-Mediated Highly Fluorescent Gold Nanoclusters and Their Use in Ultrasensitive Detection of Mercury: Synthetic and Mechanistic Aspects. ACS Omega. 2018 Dec 27;3(12):18553-18562. doi: 10.1021/acsomega.8b02505. PMID: 31458426; PMCID: PMC6643912. 4: Dubru JM, Lambrechts A. Le R 18553 dans le traitement des diarrhées aiguës du jeune enfant [R 18553 in the treatment of acute diarrhea in young children]. Rev Med Liege. 1974 Oct 1;29(19):579-81. French. PMID: 4453737. 5: Karatas Y, Kuyuldar E, Acidereli H, Gulcan M, Sen F. Polypyrrole-multi walled carbon nanotube hybrid material supported Pt NPs for hydrogen evolution from the hydrolysis of MeAB at mild conditions. Sci Rep. 2019 Dec 6;9(1):18553. doi: 10.1038/s41598-019-55030-z. PMID: 31811213; PMCID: PMC6898010. 6: Phelps RG, Jones VL, Coughlan M, Turner AN, Rees AJ. Presentation of the Goodpasture autoantigen to CD4 T cells is influenced more by processing constraints than by HLA class II peptide binding preferences. J Biol Chem. 1998 May 8;273(19):11440-7. doi: 10.1074/jbc.273.19.11440. PMID: 9565555. 7: Wang Z, Zhang M, Wang D, Song C, Liu M, Li J, Lou L, Liu Z. Failure prediction using machine learning and time series in optical network. Opt Express. 2017 Aug 7;25(16):18553-18565. doi: 10.1364/OE.25.018553. PMID: 29041054. 8: Li Z, Hu M, Zong X, He Y, Wang D, Dai L, Dong M, Zhou J, Cao H, Lv L, Chen X, Tang J. Association of telomere length and mitochondrial DNA copy number with risperidone treatment response in first-episode antipsychotic-naïve schizophrenia. Sci Rep. 2015 Dec 18;5:18553. doi: 10.1038/srep18553. PMID: 26680692; PMCID: PMC4683467. 9: Wang X, Zhao Y, Hu Y, Zhou Y, Ye X, Liu K, Bai G, Guo A, Du M, Jiang L, Wang J, Yan Z. Evaluation and validation of the diagnostic value of the apparent diffusion coefficient for differentiating early-stage endometrial carcinomas from benign mimickers at 3T MRI. Oncotarget. 2017 Jul 11;8(28):46390-46397. doi: 10.18632/oncotarget.18553. PMID: 28634318; PMCID: PMC5542275. 10: Hartinger M, Heidebrecht HJ, Schiffer S, Dumpler J, Kulozik U. Technical Concepts for the Investigation of Spatial Effects in Spiral-Wound Microfiltration Membranes. Membranes (Basel). 2019 Jul 4;9(7):80. doi: 10.3390/membranes9070080. PMID: 31277447; PMCID: PMC6680769. 11: Li Y, Liu Q, Tang JH, Wen JJ, Zhu JQ. Regulatory mechanism of mesalazine on TLR4/MyD88-dependent pathway in mouse ulcerative colitis model. Eur Rev Med Pharmacol Sci. 2019 Aug;23(15):6637-6644. doi: 10.26355/eurrev_201908_18553. PMID: 31378906. 12: Hartinger M, Heidebrecht HJ, Schiffer S, Dumpler J, Kulozik U. Milk Protein Fractionation by Means of Spiral-Wound Microfiltration Membranes: Effect of the Pressure Adjustment Mode and Temperature on Flux and Protein Permeation. Foods. 2019 May 28;8(6):180. doi: 10.3390/foods8060180. PMID: 31141922; PMCID: PMC6616940. 13: Ruiz GN, Bove LE, Corti HR, Loerting T. Pressure-induced transformations in LiCl-H2O at 77 K. Phys Chem Chem Phys. 2014 Sep 14;16(34):18553-62. doi: 10.1039/c4cp01786b. PMID: 25072395. 14: Kuroyanagi R, Nguyen LM, Tsuchizawa T, Ishikawa Y, Yamada K, Wada K. Local bandgap control of germanium by silicon nitride stressor. Opt Express. 2013 Jul 29;21(15):18553-7. doi: 10.1364/OE.21.018553. PMID: 23938727. 15: Pastan I. An NIH career: from bedside to basic research and back. J Biol Chem. 2005 May 13;280(19):18553-7. doi: 10.1074/jbc.X500002200. Epub 2005 Mar 28. PMID: 15797860. 16: Jiao D, King C, Grossfield A, Darden TA, Ren P. Simulation of Ca2+ and Mg2+ solvation using polarizable atomic multipole potential. J Phys Chem B. 2006 Sep 21;110(37):18553-9. doi: 10.1021/jp062230r. PMID: 16970483. 17: Elshal MF, Bernawi AE, Al-Ghamdy MA, Jalal JA. The association of bone mineral density and parathyroid hormone with serum magnesium in adult patients with sickle-cell anaemia. Arch Med Sci. 2012 May 9;8(2):270-6. doi: 10.5114/aoms.2012.28554. PMID: 22662000; PMCID: PMC3361039. 18: Xu SS, Chen WL, Wang YH, Li YG, Liu ZJ, Shan CH, Su ZM, Wang EB. Co- sensitization promoted light harvesting with a new mixed-addenda polyoxometalate [Cu(C12H8N2)2]2[V2W4O19]·4H2O in dye-sensitized solar cells. Dalton Trans. 2015 Nov 14;44(42):18553-62. doi: 10.1039/c5dt02992a. Epub 2015 Oct 7. PMID: 26443009. 19: Stultiens A, Ho TT, Nusgens BV, Colige AC, Deroanne CF. Rho proteins crosstalk via RhoGDIalpha: At random or hierarchically ordered? Commun Integr Biol. 2012 Jan 1;5(1):99-101. doi: 10.4161/cib.18553. PMID: 22482023; PMCID: PMC3291327. 20: Borowska J, Jones CT, Zhang H, Blacklaws J, Goulding M, Zhang Y. Functional subpopulations of V3 interneurons in the mature mouse spinal cord. J Neurosci. 2013 Nov 20;33(47):18553-65. doi: 10.1523/JNEUROSCI.2005-13.2013. PMID: 24259577; PMCID: PMC3894417.