Synonym
DO 710; DO-710; DO710
IUPAC/Chemical Name
Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-((methylamino)sulfonyl)-
InChi Key
BYONKIGBXOVRHV-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H25N3O4S/c1-4-19-9-5-6-12(19)11-18-16(20)14-10-13(24(21,22)17-2)7-8-15(14)23-3/h7-8,10,12,17H,4-6,9,11H2,1-3H3,(H,18,20)
SMILES Code
O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(NC)=O)=CC=C2OC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
355.45
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Sokoloff P, Redouane K, Brann M, Martres MP, Schwartz JC. 3H-(-)DO 710 discriminates guanine nucleotide sensitive and insensitive dopamine binding sites. Naunyn Schmiedebergs Arch Pharmacol. 1985 May;329(3):236-43. doi: 10.1007/BF00501874. PMID: 4022135.
2: Sokoloff P, Brann M, Redouane K, Martres MP, Schwartz JC, Bouthenet ML, Sales N, Mann A, Hamdi P, Wermuth CG, et al. The use of [3H](-)-DO 710 as selective dopaminergic ligand for binding and autoradiographic studies. Eur J Pharmacol. 1985 Jan 2;107(2):243-51. doi: 10.1016/0014-2999(85)90064-0. PMID: 3979426.
3: Schmidt M, Krieger JP, Giesen-Crouse EM, Imbs JL. Vascular effects of selective dopamine receptor agonists and antagonists in the rat kidney. Arch Int Pharmacodyn Ther. 1987 Apr;286(2):195-205. PMID: 2954515.
4: Barthelmebs M, Krieger JP, Grima M, Imbs JL. Existe-t-il des récepteurs D2 vasculaires rénaux? [Do renal vascular D2 receptors exist?]. Arch Mal Coeur Vaiss. 1991 Aug;84(8):1211-3. French. PMID: 1953269.
5: Leonard MN, Halliday CA, Marriott AS, Strange PG. D2 dopamine receptors in rat striatum are homogeneous as revealed by ligand-binding studies. Biochem Pharmacol. 1988 Nov 15;37(22):4335-9. doi: 10.1016/0006-2952(88)90615-6. PMID: 3196358.
