MedKoo Cat#: 534994 | Name: HB 180

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HB 180 is a bioactive chemical.

Chemical Structure

HB 180
HB 180
CAS#74680-07-2

Theoretical Analysis

MedKoo Cat#: 534994

Name: HB 180

CAS#: 74680-07-2

Chemical Formula: C23H31N5O4S

Exact Mass: 473.2097

Molecular Weight: 473.59

Elemental Analysis: C, 58.33; H, 6.60; N, 14.79; O, 13.51; S, 6.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
HB 180; HB-180; HB180
IUPAC/Chemical Name
N-(((4-Methylcyclohexyl)amino)carbonyl)-4-(2-(((methyl-2-pyridylamino)carbonyl)amino)ethyl)benzenesulphonamide
InChi Key
UIXYQZIHFQKFOZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H31N5O4S/c1-17-6-10-19(11-7-17)26-22(29)27-33(31,32)20-12-8-18(9-13-20)14-16-25-23(30)28(2)21-5-3-4-15-24-21/h3-5,8-9,12-13,15,17,19H,6-7,10-11,14,16H2,1-2H3,(H,25,30)(H2,26,27,29)
SMILES Code
O=S(C1=CC=C(CCNC(N(C)C2=NC=CC=C2)=O)C=C1)(NC(NC3CCC(C)CC3)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 473.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Antezana AM, Antezana G, Aparicio O, Noriega I, Velarde FL, Richalet JP. Pulmonary hypertension in high-altitude chronic hypoxia: response to nifedipine. Eur Respir J. 1998 Nov;12(5):1181-5. doi: 10.1183/09031936.98.12051181. PMID: 9864018. 2: Feng B, Xu WH, Gao YQ, Liu FY, Li P, Zheng SJ, Gai LY, Zhang G. Intermittent Oxygen Inhalation with Proper Frequency Improves Overall Health Conditions and Alleviates Symptoms in a Population at High Risk of Chronic Mountain Sickness with Severe Symptoms. Chin Med J (Engl). 2016 Jun 5;129(11):1322-9. doi: 10.4103/0366-6999.182831. PMID: 27231170; PMCID: PMC4894043. 3: Gastpar H, Weissgerber PW, Enzmann F, Zoltobrocki M. The inhibition of cancer cell stickiness, a model for investigation of platelet aggregation inhibitors in vivo. Effect of the sulfonyl urea derivatives, glibenclamide, gliclazide, and HB180, as well as the carboxylic acid derivative, meglitinide. Res Exp Med (Berl). 1982;180(1):75-84. doi: 10.1007/BF01852234. PMID: 6805052.