MedKoo Cat#: 462257 | Name: FMK-MEA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.

Chemical Structure

FMK-MEA
FMK-MEA
CAS#1414811-15-6

Theoretical Analysis

MedKoo Cat#: 462257

Name: FMK-MEA

CAS#: 1414811-15-6

Chemical Formula: C21H26FN5O2

Exact Mass: 399.2071

Molecular Weight: 399.47

Elemental Analysis: C, 63.14; H, 6.56; F, 4.76; N, 17.53; O, 8.01

Price and Availability

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5mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
FMK-MEA
IUPAC/Chemical Name
1-(4-amino-7-(3-((2-methoxyethyl)amino)propyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-fluoroethan-1-one
InChi Key
UPTQGXMIZXGVSC-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H26FN5O2/c1-14-4-6-15(7-5-14)17-18-20(23)25-13-26-21(18)27(19(17)16(28)12-22)10-3-8-24-9-11-29-2/h4-7,13,24H,3,8-12H2,1-2H3,(H2,23,25,26)
SMILES Code
COCCNCCCN1C2=NC=NC(N)=C2C(C3=CC=C(C)C=C3)=C1C(CF)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 399.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li D, Jin L, Alesi GN, et al. The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis. J Biol Chem. 2013;288(45):32528-32538. doi:10.1074/jbc.M113.500561.