MedKoo Cat#: 128275 | Name: ND-022

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ND-022 is an ACC inhibitor.

Chemical Structure

ND-022
ND-022
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 128275

Name: ND-022

CAS#: N/A

Chemical Formula: C20H23N2O5S

Exact Mass: 403.1328

Molecular Weight: 403.47

Elemental Analysis: C, 59.54; H, 5.75; N, 6.94; O, 19.83; S, 7.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ND-022; ND022; ND 022
IUPAC/Chemical Name
ethyl 3-(2-hydroxyethyl)-5-methyl-2,4-dioxo-1-phenethyl-2,3,4,4a-tetrahydro-1H-7l3-thieno[2,3-d]pyrimidine-6-carboxylate
InChi Key
COGNUCLSWDEZIS-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H23N2O5S/c1-3-27-19(25)16-13(2)15-17(24)21(11-12-23)20(26)22(18(15)28-16)10-9-14-7-5-4-6-8-14/h4-8,15,23H,3,9-12H2,1-2H3
SMILES Code
CCOC(C1=C(C)C2C(N(CCC3=CC=CC=C3)C(N(CCO)C2=O)=O)=[S]1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 403.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Harriman G, Greenwood J, Bhat S, Huang X, Wang R, Paul D, Tong L, Saha AK, Westlin WF, Kapeller R, Harwood HJ Jr. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1796-805. doi: 10.1073/pnas.1520686113. Epub 2016 Mar 14. PMID: 26976583; PMCID: PMC4822632.