JUN93587 | FEN1-IN-4 | CAS#1995893-58-7 | hFEN1 inhibitor

MedKoo Cat#: 462192 | Name: JUN93587

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JUN93587, also known as FEN1-IN-4, is a human flap endonuclease-1 (hFEN1) inhibitor. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

JUN93587

CAS#1995893-58-7

Theoretical Analysis

MedKoo Cat#: 462192

Name: JUN93587

CAS#: 1995893-58-7

Chemical Formula: C12H12N2O3

Exact Mass: 232.0848

Molecular Weight: 232.24

Elemental Analysis: C, 62.06; H, 5.21; N, 12.06; O, 20.67

Price and Availability

Size	Price	Availability
100mg	USD 950.00	2 Weeks
200mg	USD 1,450.00	2 Weeks
500mg	USD 2,450.00	2 Weeks
1g	USD 3,850.00	2 Weeks
2g	USD 6,450.00	2 Weeks

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Related CAS #

No Data

Synonym

FEN1-IN-4; FEN1 Inhibitor C2; JUN93587; JUN-93587; JUN 93587;

IUPAC/Chemical Name

1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

InChi Key

JAFLWTUYSKADJS-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H12N2O3/c15-11-9-3-1-2-4-10(9)13(7-8-5-6-8)12(16)14(11)17/h1-4,8,17H,5-7H2

SMILES Code

O=C(C1=C(N2CC3CC3)C=CC=C1)N(O)C2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	0.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 232.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Exell JC, Thompson MJ, Finger LD, et al. Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site. Nat Chem Biol. 2016;12(10):815-821. doi:10.1038/nchembio.2148.