Gepirone is a selective 5-HT(1A) agonist that significantly reduces depression. Gepirone is a drug of the azapirone group which is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone has been shown to be more effective than selective serotonin reuptake inhibitors (SSRIs), as this drug treats the psychiatric disorders without causing sexual dysfunction, which limits the use of SSRIs. It possesses greater selectivity for the 5-HT1A receptor than SSRIs. Clinical studies have shown that gepirone has differential action at pre- and postsynaptic 5-HT1A receptors.
MedKoo Cat#: 574361
Name: Gepirone HCl
CAS#: 83928-66-9 (HCl)
Chemical Formula: C19H30ClN5O2
Exact Mass: 0.0000
Molecular Weight: 395.93
Elemental Analysis: C, 57.64; H, 7.64; Cl, 8.95; N, 17.69; O, 8.08
The following data is based on the product molecular weight 395.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
