MedKoo Cat#: 574335 | Name: AZ10606120 dihydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZ10606120 dihydrochloride is a potent, specific P2X7 receptor antagonist that strongly inhibits tumor growth in B16-inoculated C57Bl/6 mice.

Chemical Structure

AZ10606120 dihydrochloride
AZ10606120 dihydrochloride
CAS#607378-18-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 574335

Name: AZ10606120 dihydrochloride

CAS#: 607378-18-7 (HCl)

Chemical Formula: C25H36Cl2N4O2

Exact Mass: 494.2215

Molecular Weight: 495.49

Elemental Analysis: C, 60.60; H, 7.32; Cl, 14.31; N, 11.31; O, 6.46

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
100mg USD 550.00 2 Weeks
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Synonym
AZ10606120 dihydrochloride, AZ10606120 2HCl
IUPAC/Chemical Name
N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride
InChi Key
BVFONFUUWORSPO-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H34N4O2.2ClH/c30-9-8-26-6-7-27-23-5-4-20-21(28-23)2-1-3-22(20)29-24(31)16-25-13-17-10-18(14-25)12-19(11-17)15-25;;/h1-5,17-19,26,30H,6-16H2,(H,27,28)(H,29,31);2*1H
SMILES Code
O=C(NC1=C2C=CC(NCCNCCO)=NC2=CC=C1)CC3(C4)CC5CC4CC(C5)C3.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 495.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Yan Z, et al. J Neurosci. 2010 Oct 20;30(42):14213-24. 2. Mohammed A, et al. Oncotarget. 2017 Oct 26;8(58):97822-97834. 3. Adinolfi E, et al. Cancer Res. 2012 Jun 15;72(12):2957-69. 4. Michel AD, et al. Br J Pharmacol. 2008 Feb;153(4):737-50.