(±)-AC 7954 hydrochloride | CAS# 477313-09-0 | Non-peptide urotensin-II (UT) receptor agonist

MedKoo Cat#: 574330 | Name: (±)-AC 7954 hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-AC 7954 hydrochloride is a selective nonpeptidic druglike urotensin-II receptor agonist.

Chemical Structure

(±)-AC 7954 hydrochloride

CAS# 477313-09-0

Theoretical Analysis

MedKoo Cat#: 574330

Name: (±)-AC 7954 hydrochloride

CAS#: 477313-09-0

Chemical Formula: C19H21Cl2NO2

Exact Mass: 0.0000

Molecular Weight: 366.28

Elemental Analysis: C, 62.30; H, 5.78; Cl, 19.36; N, 3.82; O, 8.74

Price and Availability

Size	Price	Availability
50mg	USD 450.00	2 Weeks
100mg	USD 750.00	2 Weeks
200mg	USD 1,350.00	2 Weeks
500mg	USD 2,950.00	2 Weeks
1g	USD 4,650.00	2 Weeks

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Related CAS #

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Synonym

(±)-AC 7954 hydrochloride; AC-7954 HCl; AC-7954 hydrochloride

IUPAC/Chemical Name

(±)-3-(4-Chlorophenyl)-3-[2-(dimethylamino)ethyl]-3,4-dihydro-1H-2-benzopyran-1-one hydrochloride

InChi Key

AJPGLOWFIBOGMH-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20ClNO2.ClH/c1-21(2)12-11-19(15-7-9-16(20)10-8-15)13-14-5-3-4-6-17(14)18(22)23-19;/h3-10H,11-13H2,1-2H3;1H

SMILES Code

O=C1C2=CC=CC=C2CC(CCN(C)C)(C3=CC=C(Cl)C=C3)O1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 366.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1) Croston et al (2002) Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 45 4950 PMID: 12408704 2) Lavecchia et al (2005) Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 48 2480 PMID: 15801838