SIRT7 inhibitor 97491 is a potent SIRT7 inhibitor that reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
MedKoo Cat#: 462174
Name: SIRT7 inhibitor 97491
CAS#: 1807758-81-1
Chemical Formula: C15H12ClN3O
Exact Mass: 285.0669
Molecular Weight: 285.73
Elemental Analysis: C, 63.05; H, 4.23; Cl, 12.41; N, 14.71; O, 5.60
The following data is based on the product molecular weight 285.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
