CAY10742 is an orally bioavailable oxadiazole antibiotic. It is active against the Gram-positive bacteria S. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, and E. faecium, including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. It reduced the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistant S. aureus (MRSA) infection.
MedKoo Cat#: 462133
Name: CAY10742
CAS#: 1649473-91-5
Chemical Formula: C22H14FN3O2
Exact Mass: 371.1070
Molecular Weight: 371.37
Elemental Analysis: C, 71.15; H, 3.80; F, 5.12; N, 11.32; O, 8.62
The following data is based on the product molecular weight 371.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
