STC-15 is a potent METTL3 inhibitor. STC-15 inhibits METTL3, an RNA methyltransferase implicated in oncology and other diseases. STC-15 has also been shown to inhibit tumor growth through mechanisms involving anti-cancer immune responses such as changes in interferon signaling and synergy with T cell checkpoint blockade. In addition, STC-15 has demonstrated efficacy in leukemia models via mechanisms such as inhibition of leukemia stem cell function.
MedKoo Cat#: 207203
Name: STC-15
CAS#: 2648257-56-9
Chemical Formula: C24H25N5O2
Exact Mass: 415.2008
Molecular Weight: 415.50
Elemental Analysis: C, 69.38; H, 6.07; N, 16.86; O, 7.70
The following data is based on the product molecular weight 415.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |