MedKoo Cat#: 534649 | Name: Pyricarbate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyricarbate is a drug that has been given by mouth in the treatment of atherosclerosis and other vascular disorders, hyperlipidemias, and thrombo-embolic disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1408)

Chemical Structure

Pyricarbate
Pyricarbate
CAS#1882-26-4

Theoretical Analysis

MedKoo Cat#: 534649

Name: Pyricarbate

CAS#: 1882-26-4

Chemical Formula: C11H15N3O4

Exact Mass: 253.1063

Molecular Weight: 253.26

Elemental Analysis: C, 52.17; H, 5.97; N, 16.59; O, 25.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Pyricarbate
IUPAC/Chemical Name
2,6-Pyridinediyldimethylene bis(methylcarbamate)
InChi Key
YEKQSSHBERGOJK-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H15N3O4/c1-12-10(15)17-6-8-4-3-5-9(14-8)7-18-11(16)13-2/h3-5H,6-7H2,1-2H3,(H,12,15)(H,13,16)
SMILES Code
O=C(OCC1=NC(COC(NC)=O)=CC=C1)NC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 253.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sée A, Bouvry M. Hépatite au pyricarbate [Hepatitis from pyricarbate]. Gastroenterol Clin Biol. 1984 Jun-Jul;8(6-7):579. French. PMID: 6745580. 2: Biour M, Barbare JC, Begaud B, Furet Y, Grange JD, Cheymol G. Hépatites aiguës dues au pyricarbate (Angioxine). A propos de 5 cas [Acute hepatitis due to pyricarbate (Angioxine). Apropos of 5 cases]. Therapie. 1984 Sep- Oct;39(5):531-6. French. PMID: 6506010. 3: Walton KW, Thomas C, Dunkerley DJ. The pathogenesis of xanthomata. J Pathol. 1973 Apr;109(4):271-89. doi: 10.1002/path.1711090402. PMID: 4578583. 4: Numano F. Chemotherapy of atherosclerosis. Jpn Circ J. 1980 Jan;44(1):55-68. doi: 10.1253/jcj.44.55. PMID: 6245288. 5: Apport de l'Angioxine dans la protection vasculaire du diabétique [Contribution of angioxine to the vascular protection of the diabetic]. Journ Annu Diabetol Hotel Dieu. 1976 May:319-27. French. PMID: 796526. 6: Romics L. Drug treatment of hyperlipoproteinaemia. Ther Hung. 1983;31(4):152-60. PMID: 6400456. 7: Sassard J, Bernard N, Legheand J, Cuisinaud G, Traeger J. Pharmacokinetics and bioavailability of pyridinol carbamate in humans. J Pharm Sci. 1979 Sep;68(9):1190-1. doi: 10.1002/jps.2600680939. PMID: 501551. 8: Szén T, Szöllösy A. Uber die Synthese von Pyridinolcarbamat [Synthesis of pyridinolcarbamate]. Arch Pharm (Weinheim). 1977 Sep;310(9):759-62. German. doi: 10.1002/ardp.19773100912. PMID: 921516. 9: Margolis MG. Angioprotektory v oftal'mologii [Angioprotectors in ophthalmology]. Oftalmol Zh. 1979;34(5):314-8. Russian. PMID: 503433. 10: Chekova LP, Trubnikov VI, Shemiakin FM. Rol' sorbentov v gazokhromatograficheskom analize geterotsiklicheskikh azotsoderzhashchikh lekarstvennykh veshchestv [Role of sorbents in the gas chromatographic analysis of heterocyclic nitrogen-containing drug substances]. Farmatsiia. 1975 Jul- Aug;24(4):77-84. Russian. PMID: 767148.