MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 462060 | Name: Tembetarine iodide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tembetarine is a tembetarine obtained by methylation of the tertiary amino function of (R)-reticuline. It has a role as a plant metabolite. It is a benzylisoquinoline alkaloid and a tembetarine. It derives from a (S)-reticuline. It is an enantiomer of a (R)-tembetarine.

Chemical Structure

Tembetarine iodide
Tembetarine iodide
CAS#77794-96-8 (iodide)

Theoretical Analysis

MedKoo Cat#: 462060

Name: Tembetarine iodide

CAS#: 77794-96-8 (iodide)

Chemical Formula: C20H26INO4

Exact Mass: 344.1856

Molecular Weight: 471.34

Elemental Analysis: C, 50.97; H, 5.56; I, 26.92; N, 2.97; O, 13.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
2824-94-4 (chloride) 18446-73-6 (cation) 77794-96-8 (iodide) 4201-99-4 (hydroxide) 485-19-8 (Reticuline)
Synonym
(S)-tembetarine; Tembetarine; Tembetarine iodide; (+)-Tembetarine iodide; N-Methylreticulinium iodide; d-Tembetarine iodide;
IUPAC/Chemical Name
Isoquinolinium, 1,2,3,4-tetrahydro-7-hydroxy-1-((3-hydroxy-4-methoxyphenyl)methyl)-6-methoxy-2,2-dimethyl-, (S)-, iodide
InChi Key
YHESZQUPLJBSNE-NTISSMGPSA-N
InChi Code
InChI=1S/C20H25NO4.HI/c1-21(2)8-7-14-11-20(25-4)18(23)12-15(14)16(21)9-13-5-6-19(24-3)17(22)10-13;/h5-6,10-12,16H,7-9H2,1-4H3,(H-,22,23);1H/t16-;/m0./s1
SMILES Code
C[N+]1(C)[C@@H](CC2=CC=C(OC)C(O)=C2)C3=C(C=C(OC)C(O)=C3)CC1.[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 471.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Isolation and Characterization of Reticuline N-Methyltransferase Involved in Biosynthesis of the Aporphine Alkaloid Magnoflorine in Opium Poppy Jeremy S. Morris, Peter J. Facchini J Biol Chem. 2016 Nov 4; 291(45): 23416–23427. Published online 2016 Sep 15. doi: 10.1074/jbc.M116.750893 PMCID: PMC5095398 2: Studies on the Alkaloids of the Bark of Magnolia officinalis: Isolation and On-line Analysis by HPLC-ESI-MSn Renyi Yan, Weihao Wang, Jian Guo, Hongliang Liu, Jianyong Zhang, Bin Yang Molecules. 2013 Jul; 18(7): 7739 7750. Published online 2013 Jul 3. doi: 10.3390/molecules18077739 PMCID: PMC6270518 3: Study on the Material Basis of Houpo Wenzhong Decoction by HPLC Fingerprint, UHPLC-ESI-LTQ-Orbitrap-MS, and Network Pharmacology Juyuan Luo, Gongsen Chen, Donghan Liu, Yan Wang, Qi Qi, Haiyan Hu, Pengyue Li, Jie Bai, Shouying Du, Yang Lu, Yuming Wang, Cun Liu Molecules. 2019 Jul; 24(14): 2561. Published online 2019 Jul 14. doi: 10.3390/molecules24142561 PMCID: PMC6681077 4: Rapid Characterization and Identification of Non-Diterpenoid Constituents in Tinospora sinensis by HPLC-LTQ-Orbitrap MSn Qi-Shu Jiao, Lu-Lu Xu, Jia-Yu Zhang, Zi-Jian Wang, Yan-Yan Jiang, Bin Liu Molecules. 2018 Feb; 23(2): 274. Published online 2018 Jan 28. doi: 10.3390/molecules23020274 PMCID: PMC6017642 5: Novel findings to the biosynthetic pathway of magnoflorine and taspine through transcriptomic and metabolomic analysis of Croton draco (Euphorbiaceae) Anahí Canedo-Téxon, Feliza Ramón-Farias, Juan Luis Monribot-Villanueva, Emanuel Villafán, Alexandro Alonso-Sánchez, Claudia Anahí Pérez-Torres, Guillermo Ángeles, José Antonio Guerrero-Analco, Enrique Ibarra-Laclette BMC Plant Biol. 2019; 19: 560. Published online 2019 Dec 18. doi: 10.1186/s12870-019-2195-y PMCID: PMC6921603 6: Antibacterial activities of Fagara macrophylla, Canarium schweinfurthii, Myrianthus arboreus, Dischistocalyx grandifolius and Tragia benthamii against multi-drug resistant Gram-negative bacteria Jackson A. Seukep, Bonaventure Ngadjui, Victor Kuete Springerplus. 2015; 4: 567. Published online 2015 Oct 1. doi: 10.1186/s40064-015-1375-y PMCID: PMC4627964 7: Comparison of Anticancer Activity and HPLC-DAD Determination of Selected Isoquinoline Alkaloids from Thalictrum foetidum, Berberis sp. and Chelidonium majus Extracts Anna Petruczynik, Tomasz Tuzimski, Tomasz Plech, Justyna Misiurek, Karolina Szalast, Grażyna Szymczak Molecules. 2019 Oct; 24(19): 3417. Published online 2019 Sep 20. doi: 10.3390/molecules24193417 PMCID: PMC6803846 8: Ethnomedicinal Investigation of Medicinal Plants of Chakrata Region (Uttarakhand) Used in the Traditional Medicine for Diabetes by Jaunsari Tribe Ankit Kumar, Sonali Aswal, Ashutosh Chauhan, Ruchi Badoni Semwal, Abhimanyu Kumar, Deepak Kumar Semwal Nat Prod Bioprospect. 2019 Jun; 9(3): 175–200. Published online 2019 Apr 9. doi: 10.1007/s13659-019-0202-5 PMCID: PMC6538708 9: Phellodendri Cortex: A Phytochemical, Pharmacological, and Pharmacokinetic Review Yue Sun, George Binh Lenon, Angela Wei Hong Yang Evid Based Complement Alternat Med. 2019; 2019: 7621929. Published online 2019 Apr 1. doi: 10.1155/2019/7621929 PMCID: PMC6463642 10: Medicinal plants commonly used against cancer in traditional medicine formulae in Sri Lanka Anchala I. Kuruppu, Priyani Paranagama, Charitha L. Goonasekara Saudi Pharm J. 2019 May; 27(4): 565–573. Published online 2019 Feb 7. doi: 10.1016/j.jsps.2019.02.004 PMCID: PMC6488922

View History

CP26

CP26