Valeroyl phenytoin | CAS#22506-76-9 | DPH derivative

MedKoo Cat#: 461996 | Name: Valeroyl phenytoin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Valeroyl phenytoin is a derivative of phenytoin (DPH) that is synthesized by the reaction at 3 position of hydantoin ring with valeric acid. It has shown a much higher lipid solubility than that of DPH.

Chemical Structure

Valeroyl phenytoin

CAS#22506-76-9

Theoretical Analysis

MedKoo Cat#: 461996

Name: Valeroyl phenytoin

CAS#: 22506-76-9

Chemical Formula: C20H20N2O3

Exact Mass: 336.1474

Molecular Weight: 336.39

Elemental Analysis: C, 71.41; H, 5.99; N, 8.33; O, 14.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Valeroyl phenytoin; Valeroyl dph; VADPH

IUPAC/Chemical Name

3-pentanoyl-5,5-diphenylimidazolidine-2,4-dione

InChi Key

DYVNLCJHGUOASO-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H20N2O3/c1-2-3-14-17(23)22-18(24)20(21-19(22)25,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-13H,2-3,14H2,1H3,(H,21,25)

SMILES Code

CCCCC(N1C(NC(C2=CC=CC=C2)(C3=CC=CC=C3)C1=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 336.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ogiso T, Iwaki M, Tanino T, Muraoka O, Tanabe G. Pharmacokinetic analysis of phenytoin and its derivatives in plasma and brain in rats. Biol Pharm Bull. 1993 Oct;16(10):1025-30. PubMed PMID: 8287032. 2: Ogiso T, Tanino T, Iwaki M, Muraoka O, Tanabe G. Physicochemical and hydrolytic characteristics of phenytoin derivatives. Biol Pharm Bull. 1994 Oct;17(10):1425-9. PubMed PMID: 7874071.