Related CAS #
6253-07-2; 3784-99-4 (iodide)
Synonym
Stilbazium iodide; BW-61-32; BW 61 32; BW6132; BW 61-32; BW 6132; NSC-89239; NSC89239; NSC 89239; Monopar
IUPAC/Chemical Name
1-Ethyl-2,6-bis(2-(4-(1-pyrrolidinyl)phenyl)ethenyl)pyridinium iodide
InChi Key
BYIRBDUHSVOFLU-UHFFFAOYSA-M
InChi Code
InChI=1S/C31H36N3.HI/c1-2-34-30(20-14-26-10-16-28(17-11-26)32-22-3-4-23-32)8-7-9-31(34)21-15-27-12-18-29(19-13-27)33-24-5-6-25-33;/h7-21H,2-6,22-25H2,1H3;1H/q+1;/p-1
SMILES Code
CC[N+]1=C(/C=C/C2=CC=C(N3CCCC3)C=C2)C=CC=C1/C=C/C4=CC=C(N5CCCC5)C=C4.[I-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
577.55
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: BURROWS RB, HUNT GR. Stilbazium iodide as an anthelmintic. I. Against Syphacia obvelata in mice. J Parasitol. 1962 Oct;48:767-8. PMID: 14017190.
2: BURROWS RB, LILLIS WG. Stilbazium iodide as an anthelmintic. II. Against various nematodes of dogs and cats. J Parasitol. 1962 Oct;48:769-71. PMID: 14017191.
3: Beck JW, García Laverde A, Hartog EM, Shaner AL. Empleo de la técnica de recuento de huevos de Ritchie-Frick en el estudio de la efectividad del antihelmíntico Monopar (yoduro de stilbazium) [Use of the Ritchie-Frick egg counting technic in the study of the effectiveness of the anthelmintic Monopar (stilbazium iodide)]. Rev Fac Med Univ Nac Colomb. 1965 Jan-Mar;33(1):33-6. Spanish. PMID: 5899996.
4: Campos R, Amato Neto V, de Vasconcellos AT, de Wanderley RA. Tratamento da ascaridíase e da tricocefalíase pelo iodeto de estilbásio [Treatment of ascariasis and trichocephaliasis with stilbazium iodide]. Hospital (Rio J). 1967 Mar;71(3):703-9. Portuguese. PMID: 5304809.
5: Campos R, Amato Neto V, Levi GC, Vilela E, Gomes MC. Pamoato de pirvínio e iodeto de estilbásio no tratamento de crianças com enterobíase. Observações em habitação coletiva com duas repetições periódicas das administrações [Pyrivinism and and stilbazium iodide in the treatment of children with enterobiasis. Observations in a collective residency after 2 periodic administrations]. Hospital (Rio J). 1969 Feb;75(2):499-504. Portuguese. PMID: 5311629.
6: HUANG WH, BROWN HW. CLINICAL TRIALS OF STILBAZIUM IODIDE (MONOPAR) IN THE TREATMENT OF TRICHURIS AND ASCARIS INFECTIONS. Am J Trop Med Hyg. 1964 Jan;13:54-6. doi: 10.4269/ajtmh.1964.13.54. PMID: 14106054.
7: CANTOR DS. TRATAMIENTO DE LA ENTEROBIASIS CON IODURO DE STILBAZIUM [TREATMENT OF ENTEROBIASIS WITH STILBAZIUM IODIDE]. Bol Chil Parasitol. 1964 Jul- Sep;19:87-8. Spanish. PMID: 14205513.
8: HUNT GR, BURROWS RB. STILBAZIUM IODIDE IN THE MASS TREATMENT OF MICE INFECTED WITH SYPHACIA OBVELATA. J Parasitol. 1963 Dec;49:1019-20. PMID: 14084181.
9: JEFFERY GM, RONDEAU EA, HARRISON AJ, PHIFER KO. EFFECT OF STILBAZIUM IODIDE ON ENTEROBIUS VERMICULARIS AND OTHER INTESTINAL HELMINTHS. J Parasitol. 1963 Aug;49:639-41. PMID: 14050241.
10: WAGNER ED. THE SINGLE DOSE TREATMENT OF ENTEROBIASIS WITH STILBAZIUM IODIDE (MONOPAR). J Parasitol. 1963 Dec;49:1021-2. PMID: 14084182.