AV-15a is a novel, highly potent p53-MDM2 inhibitor with an IC50 value of 0.08 nmol/L, displaying excellent oral efficacy in the human SJSA1-based xenograft model.
MedKoo Cat#: 533708
Name: AV-15a
CAS#: N/A
Chemical Formula: C28H27Cl2N5O3
Exact Mass: 551.1491
Molecular Weight: 552.46
Elemental Analysis: C, 60.88; H, 4.93; Cl, 12.83; N, 12.68; O, 8.69
The following data is based on the product molecular weight 552.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
