MedKoo Cat#: 461976 | Name: Balofloxacin dihydrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Balofloxacin dehydrate is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.

Chemical Structure

Balofloxacin dihydrate
Balofloxacin dihydrate
CAS#151060-21-8 (hydrate)

Theoretical Analysis

MedKoo Cat#: 461976

Name: Balofloxacin dihydrate

CAS#: 151060-21-8 (hydrate)

Chemical Formula: C20H28FN3O6

Exact Mass: 0.0000

Molecular Weight: 425.46

Elemental Analysis: C, 56.46; H, 6.63; F, 4.47; N, 9.88; O, 22.56

Price and Availability

Size Price Availability Quantity
1g USD 350.00 2 Weeks
2g USD 550.00 2 Weeks
5g USD 950.00 2 Weeks
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Synonym
Balofloxacin dihydrate; Balofloxacin hydrate
IUPAC/Chemical Name
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-(methylamino)piperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid dihydrate
InChi Key
WEGNYJXOCPJAPS-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H24FN3O4.2H2O/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27;;/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27);2*1H2
SMILES Code
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(NC)CCC4)=C3OC)C1=O)O.[H]O[H].[H]O[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 425.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakagawa T, Ishigai M, Kato M, Hayakawa N, Kinoshita H, Okutomi T, Ohkubo K, Okazaki A. Pharmacokinetics of the new fluoroquinolone balofloxacin in mice, rats, and dogs. Arzneimittelforschung. 1995 Jun;45(6):719-22. PubMed PMID:7646579. 2: Nakagawa T, Ishigai M, Hiramatsu Y, Kinoshita H, Ishitani Y, Ohkubo K, Okazaki A. Determination of the new fluoroquinolone balofloxacin and its metabolites in biological fluids by high performance liquid chromatography. Arzneimittelforschung. 1995 Jun;45(6):716-8. PubMed PMID: 7646578.