Xeruborbactam, also known as QPX7728, is an ultrabroad-spectrum inhibitor of serine and metallo-β-lactamases. This compound displays a remarkably broad spectrum of inhibition, including class B and class D enzymes, and is little affected by porin modifications and efflux. QPX7728 is a promising agent for use in combination with a β-lactam antibiotic for the treatment of a wide range of multidrug resistant Gram-negative bacterial infections, by both intravenous and oral administration.
MedKoo Cat#: 593173
Name: Xeruborbactam
CAS#: 2170834-63-4 (free acid)
Chemical Formula: C10H8BFO4
Exact Mass: 222.0500
Molecular Weight: 221.98
Elemental Analysis: C, 54.11; H, 3.63; B, 4.87; F, 8.56; O, 28.83
The following data is based on the product molecular weight 221.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
