MedKoo Cat#: 555732 | Name: GSK2983559 free acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK2983559 (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor.

Chemical Structure

GSK2983559 free acid
GSK2983559 free acid
CAS#1579965-12-0 (free acid)

Theoretical Analysis

MedKoo Cat#: 555732

Name: GSK2983559 free acid

CAS#: 1579965-12-0 (free acid)

Chemical Formula: C21H23N4O7PS2

Exact Mass: 538.0746

Molecular Weight: 538.53

Elemental Analysis: C, 46.84; H, 4.31; N, 10.40; O, 20.80; P, 5.75; S, 11.91

Price and Availability

Size Price Availability Quantity
5mg USD 250.00 2 Weeks
10mg USD 450.00 2 Weeks
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Synonym
GSK2983559; GSK-2983559; GSK 2983559; GSK2983559 free acid;
IUPAC/Chemical Name
2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate
InChi Key
MJLYDVMFNHZMLV-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H23N4O7PS2/c1-21(2,3)35(29,30)19-9-14-15(10-17(19)31-6-7-32-33(26,27)28)22-11-23-20(14)25-13-4-5-18-16(8-13)24-12-34-18/h4-5,8-12H,6-7H2,1-3H3,(H,22,23,25)(H2,26,27,28)
SMILES Code
CC(C)(S(C1=CC2=C(NC3=CC4=C(C=C3)SC=N4)N=CN=C2C=C1OCCOP(O)(O)=O)(=O)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 538.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Sheridan C. Publisher Correction: Death by inflammation: drug makers chase the master controller. Nat Biotechnol. 2019;37(4):480. doi:10.1038/s41587-019-0082-6