JMX0312 is a salicylamide derivative used as a potent inhibitor of HAdV infection. JMX0312 showed significantly improved anti-HAdV activities with nanomolar to submicromolar IC50 values and high selectivity indexes (SI > 100), indicating better safety windows, compared to those of the lead compound niclosamide.
MedKoo Cat#: 593169
Name: JMX0312
CAS#: 439144-75-9
Chemical Formula: C14H8ClF4NO2
Exact Mass: 333.0180
Molecular Weight: 333.67
Elemental Analysis: C, 50.40; H, 2.42; Cl, 10.62; F, 22.78; N, 4.20; O, 9.59
The following data is based on the product molecular weight 333.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
