UNC-926 is a selective antagonist of the methyl-lysine binding protein L3MBTL1, a member of the malignant brain tumor (MBT) domain-containing protein family. It binds to the MBT domain of L3MBTL1 with a dissociation constant (Kd) of 3.9 μM, inhibiting its interaction with monomethylated histone H4 lysine 20 (H4K20me1).
MedKoo Cat#: 555216
Name: UNC-926 free base
CAS#: 1184136-10-4 (free base)
Chemical Formula: C16H21BrN2O
Exact Mass: 336.0837
Molecular Weight: 337.26
Elemental Analysis: C, 56.98; H, 6.28; Br, 23.69; N, 8.31; O, 4.74
The following data is based on the product molecular weight 337.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
