MedKoo Cat#: 533778 | Name: ML-SA5
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ML-SA5 is a novel mucolipin 1 (ML1) agonist, inducing lysosomal Ca2+ release, ameliorating muscular dystrophies and activating TFEB to correct lysosomal insufficiency in mdx mice.

Chemical Structure

ML-SA5
ML-SA5
CAS#2418670-70-7

Theoretical Analysis

MedKoo Cat#: 533778

Name: ML-SA5

CAS#: 2418670-70-7

Chemical Formula: C19H24ClN3O4S2

Exact Mass: 457.0897

Molecular Weight: 457.99

Elemental Analysis: C, 49.83; H, 5.28; Cl, 7.74; N, 9.18; O, 13.97; S, 14.00

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 7,650.00 2 Weeks
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Related CAS #
No Data
Synonym
ML-SA5; ML SA5; MLSA5
IUPAC/Chemical Name
N1-(3-Chloro-2-(piperidin-1-yl)phenyl)-N4,N4-dimethylbenzene-1,4-disulfonamide
InChi Key
YPPWKTIVYUTTEH-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H24ClN3O4S2/c1-22(2)29(26,27)16-11-9-15(10-12-16)28(24,25)21-18-8-6-7-17(20)19(18)23-13-4-3-5-14-23/h6-12,21H,3-5,13-14H2,1-2H3
SMILES Code
O=S(C1=CC=C(S(=O)(N(C)C)=O)C=C1)(NC2=CC=CC(Cl)=C2N3CCCCC3)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 457.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhang X, Cheng X, Yu L, et al. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy. Nat Commun. 2016;7:12109. Published 2016 Jun 30. doi:10.1038/ncomms12109