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MedKoo Cat#: 412119 | Name: Clobenzorex hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clobenzorex hydrochloride is a stimulant drug of the phenethylamine and amphetamine chemical classes used as an appetite suppressant.

Chemical Structure

Clobenzorex hydrochloride
Clobenzorex hydrochloride
CAS#5843-53-8

Theoretical Analysis

MedKoo Cat#: 412119

Name: Clobenzorex hydrochloride

CAS#: 5843-53-8

Chemical Formula: C16H19Cl2N

Exact Mass:

Molecular Weight: 296.24

Elemental Analysis: C, 64.87; H, 6.47; Cl, 23.93; N, 4.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Clobenzorex hydrochloride; BA7205; BA-7205; BA 7205
IUPAC/Chemical Name
(+)-N-(o-Chlorobenzyl)-alpha-methylphenethylamine hydrochloride
InChi Key
InChI=1S/C16H18ClN.ClH/c1-13(11-14-7-3-2-4-8-14)18-12-15-9-5-6-10-16(15)17;/h2-10,13,18H,11-12H2,1H3;1H
InChi Code
InChI=1S/C16H18ClN.ClH/c1-13(11-14-7-3-2-4-8-14)18-12-15-9-5-6-10-16(15)17;/h2-10,13,18H,11-12H2,1H3;1H
SMILES Code
CC(NCC1=CC=CC=C1Cl)CC2=CC=CC=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
In the United States, clobenzorex tablets (among other varieties of stimulants, such as amphetamine) have been used by athletes who ingest the drug to reduce fatigue, increase attention, and improve reaction times during athletic activities.

Preparing Stock Solutions

The following data is based on the product molecular weight 296.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Role of substance P on histamine H(3) antagonist-induced scratching behavior in mice. J Pharmacol Sci. 2006 Apr;100(4):297-302. doi: 10.1254/jphs.fpj05028x. Epub 2006 Apr 7. PMID: 16603804. 7: Tardieu S, Poirier Y, Micallef J, Blin O. Amphetamine-like stimulant cessation in an abusing patient treated with bupropion. Acta Psychiatr Scand. 2004 Jan;109(1):75-7; discussion 77-8. doi: 10.1111/j.0001-690x.2004.t01-1-00196.x. PMID: 14674962. 8: Cody JT. Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results. J Occup Environ Med. 2002 May;44(5):435-50. doi: 10.1097/00043764-200205000-00012. PMID: 12024689. 9: Kraemer T, Maurer HH. Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives. Ther Drug Monit. 2002 Apr;24(2):277-89. doi: 10.1097/00007691-200204000-00009. PMID: 11897973. 10: Cody JT, Valtier S. Amphetamine, clobenzorex, and 4-hydroxyclobenzorex levels following multidose administration of clobenzorex. J Anal Toxicol. 2001 Apr;25(3):158-65. doi: 10.1093/jat/25.3.158. PMID: 11327347. 11: Valtier S, Cody JT. Differentiation of clobenzorex use from amphetamine abuse using the metabolite 4-hydroxyclobenzorex. J Anal Toxicol. 2000 Oct;24(7):606-13. doi: 10.1093/jat/24.7.606. PMID: 11043667. 12: Musshoff F. Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine. Drug Metab Rev. 2000 Feb;32(1):15-44. doi: 10.1081/dmr-100100562. PMID: 10711406. 13: Cody JT, Valtier S. A gas chromatography-mass spectrometry method for the quantitation of clobenzorex. J Anal Toxicol. 1999 Nov-Dec;23(7):603-8. doi: 10.1093/jat/23.7.603. PMID: 10595847. 14: Baden KL, Valtier S, Cody JT. Metabolic production of amphetamine following multidose administration of clobenzorex. J Anal Toxicol. 1999 Oct;23(6):511-7. doi: 10.1093/jat/23.6.511. PMID: 10517559. 15: Ku YR, Chang YS, Wen KC, Ho LK. Analysis and confirmation of synthetic anorexics in adulterated traditional Chinese medicines by high-performance capillary electrophoresis. J Chromatogr A. 1999 Jul 2;848(1-2):537-43. doi: 10.1016/s0021-9673(99)00475-6. PMID: 10427768. 16: Valtier S, Cody JT. Metabolic production of amphetamine following administration of clobenzorex. J Forensic Sci. 1999 Jan;44(1):17-22. PMID: 9987865. 17: Baumevieille M, Haramburu F, Bégaud B. Abuse of prescription medicines in southwestern France. Ann Pharmacother. 1997 Jul-Aug;31(7-8):847-50. doi: 10.1177/106002809703100706. PMID: 9220042. 18: Maurer HH, Kraemer T, Ledvinka O, Schmitt CJ, Weber AA. Gas chromatography- mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) in toxicological analysis. Studies on the detection of clobenzorex and its metabolites within a systematic toxicological analysis procedure by GC-MS and by immunoassay and studies on the detection of alpha- and beta-amanitin in urine by atmospheric pressure ionization electrospray LC-MS. J Chromatogr B Biomed Sci Appl. 1997 Feb 7;689(1):81-9. doi: 10.1016/s0378-4347(96)00348-9. PMID: 9061484. 19: Young R, Darmani NA, Elder EL, Dumas D, Glennon RA. Clobenzorex: evidence for amphetamine-like behavioral actions. Pharmacol Biochem Behav. 1997 Feb;56(2):311-6. doi: 10.1016/s0091-3057(96)00329-2. PMID: 9050090. 20: de la Torre R, Badia R, Gonzàlez G, García M, Pretel MJ, Farré M, Segura J. Cross-reactivity of stimulants found in sports drug testing by two fluorescence polarization immunoassays. J Anal Toxicol. 1996 May-Jun;20(3):165-70. doi: 10.1093/jat/20.3.165. PMID: 8735197.