MJN68390, also known as Procaspase-8 Inhibitor 63-R, is a novel selective procaspase-8 (Pro-C8) Inhibitor covalently binding the zymogen, or inactive precursor (pro-form), of caspase-8, but not other caspases. This product was first reported in Nature (London, United Kingdom) (2016), 534(7608), 570-574. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 533740
Name: MJN68390
CAS#: 1956368-39-0 (R-Isomer)
Chemical Formula: C24H28ClN3O3
Exact Mass: 441.1819
Molecular Weight: 441.96
Elemental Analysis: C, 65.22; H, 6.39; Cl, 8.02; N, 9.51; O, 10.86
The following data is based on the product molecular weight 441.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
