XR 1853 | CAS#158944-02-6 | modulator

MedKoo Cat#: 585449 | Name: XR 1853

Description:

WARNING: This product is for research use only, not for human or veterinary use.

XR 1853 is a low molecular weight modulator of human plasminogen activator inhibitor-1 activity.

Chemical Structure

XR 1853

CAS#158944-02-6

Theoretical Analysis

MedKoo Cat#: 585449

Name: XR 1853

CAS#: 158944-02-6

Chemical Formula: C22H23N3O3

Exact Mass: 377.1739

Molecular Weight: 377.44

Elemental Analysis: C, 70.01; H, 6.14; N, 11.13; O, 12.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

XR 1853; XR1853; XR-1853

IUPAC/Chemical Name

3-((4-(2-(Dimethylamino)ethoxy)phenyl)methylene)-6-(phenylmethylene)-2,5-piperazinedione

InChi Key

SKAOOZAHHYQXKN-PXXPDPNMSA-N

InChi Code

InChI=1S/C22H23N3O3/c1-25(2)12-13-28-18-10-8-17(9-11-18)15-20-22(27)23-19(21(26)24-20)14-16-6-4-3-5-7-16/h3-11,14-15H,12-13H2,1-2H3,(H,23,27)(H,24,26)/b19-14+,20-15+

SMILES Code

O=C(/C(NC/1=O)=C\C2=CC=C(OCCN(C)C)C=C2)NC1=C\C3=CC=CC=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 377.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gils A, Stassen JM, Nar H, Kley JT, Wienen W, Ries UJ, Declerck PJ. Characterization and comparative evaluation of a novel PAI-1 inhibitor. Thromb Haemost. 2002 Jul;88(1):137-43. PubMed PMID: 12152654. 2: Charlton PA, Faint RW, Bent F, Bryans J, Chicarelli-Robinson I, Mackie I, Machin S, Bevan P. Evaluation of a low molecular weight modulator of human plasminogen activator inhibitor-1 activity. Thromb Haemost. 1996 May;75(5):808-15. PubMed PMID: 8725728.