Avermectin B1a monosaccharide | CAS# 71831-09-9 | Anthelmintic

MedKoo Cat#: 574284 | Name: Avermectin B1a monosaccharide

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a. Avermectin B1A is a macrocyclic lactone disaccharide anthelmintic agent that binds to high and low affinity sites on the mammalian GABAA receptor. Binding to the high affinity site activates the receptor to increase chloride influx, while binding to the low affinity site blocks the channel. Avermectin B1a inhibits binding of the glycine receptor antagonist strychnine to membranes and the solubilized receptor from rat spinal cord. Formulations containing avermectin B1a (>80%) and avermectin B1b (~20%) are used in insecticides and veterinary anthelmintic formulas as abamectin.

Chemical Structure

Avermectin B1a monosaccharide

CAS#71831-09-9

Theoretical Analysis

MedKoo Cat#: 574284

Name: Avermectin B1a monosaccharide

CAS#: 71831-09-9

Chemical Formula: C41H60O11

Exact Mass: 728.4136

Molecular Weight: 728.92

Elemental Analysis: C, 67.56; H, 8.30; O, 24.14

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 580.00	2 Weeks

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Synonym

Avermectin B1a monosaccharide

IUPAC/Chemical Name

4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a

InChi Key

ZBVWYDMYMRLKIV-OESCZRLOSA-N

InChi Code

InChI=1S/C41H60O11/c1-9-22(2)37-25(5)15-16-40(52-37)20-30-18-29(51-40)14-13-24(4)36(50-33-19-32(46-8)35(43)27(7)48-33)23(3)11-10-12-28-21-47-38-34(42)26(6)17-31(39(44)49-30)41(28,38)45/h10-13,15-17,22-23,25,27,29-38,42-43,45H,9,14,18-21H2,1-8H3/b11-10+,24-13+,28-12+/t22-,23-,25-,27-,29+,30-,31-,32-,33-,34+,35-,36-,37+,38+,40+,41+/m0/s1

SMILES Code

C/C([C@@H](O[C@@]1([H])C[C@H](OC)[C@@H](O)[C@H](C)O1)[C@@H](C)/C=C/C=C(CO2)/[C@@]([C@@]2([H])[C@H](O)C(C)=C3)(O)[C@]3([H])C4=O)=C\C[C@]5([H])C[C@@](O4)([H])C[C@]6(C=C[C@H](C)[C@]([C@@H](C)CC)([H])O6)O5

Appearance

Solid powder

Purity

>85% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 728.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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