MRK-740 is a novel potent (IC50: 80 ± 16 nM), selective and cell-active PRDM9 inhibitor, specifically and directly inhibiting H3K4 methylation at endogenous PRDM9 target loci.
MedKoo Cat#: 533569
Name: MRK-740 HCl
CAS#: MRK-740 HCl
Chemical Formula: C25H33ClN6O3
Exact Mass: 464.2536
Molecular Weight: 501.03
Elemental Analysis: C, 59.93; H, 6.64; Cl, 7.08; N, 16.77; O, 9.58
The following data is based on the product molecular weight 501.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
