MedKoo Cat#: 533544 | Name: JNJ-42226314
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ-42226314 is a novel, reversible, selective and potent monoacylglycerol lipase (MAGL) inhibitor.

Chemical Structure

JNJ-42226314
JNJ-42226314
CAS#1252765-13-1

Theoretical Analysis

MedKoo Cat#: 533544

Name: JNJ-42226314

CAS#: 1252765-13-1

Chemical Formula: C26H24FN5O2S

Exact Mass: 489.1635

Molecular Weight: 489.57

Elemental Analysis: C, 63.79; H, 4.94; F, 3.88; N, 14.31; O, 6.54; S, 6.55

Price and Availability

Size Price Availability Quantity
1mg USD 250.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
JNJ-42226314; JNJ 42226314; JNJ42226314
IUPAC/Chemical Name
[1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone
InChi Key
IVOACCSOISMVBL-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H24FN5O2S/c27-20-2-4-21(5-3-20)32-9-7-18-15-19(1-6-23(18)32)25(33)31-16-22(17-31)29-10-12-30(13-11-29)26(34)24-28-8-14-35-24/h1-9,14-15,22H,10-13,16-17H2
SMILES Code
O=C(C1=CC2=C(N(C3=CC=C(F)C=C3)C=C2)C=C1)N4CC(N5CCN(C(C6=NC=CS6)=O)CC5)C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 489.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL