VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
MedKoo Cat#: 533543
Name: VTP50469 mesylate
CAS#: 2169919-27-9 (mesylate)
Chemical Formula: C33H51FN6O7S2
Exact Mass: 630.3364
Molecular Weight: 726.92
Elemental Analysis: C, 54.53; H, 7.07; F, 2.61; N, 11.56; O, 15.41; S, 8.82
The following data is based on the product molecular weight 726.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
