Wy 27569 | CAS#103417-69-2 | antithrombotic-antihypertensive

MedKoo Cat#: 585431 | Name: Wy 27569

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Wy 27569 is is a combined calcium channel blocker and thromboxane synthetase inhibitor.

Chemical Structure

Wy 27569

CAS#103417-69-2

Theoretical Analysis

MedKoo Cat#: 585431

Name: Wy 27569

CAS#: 103417-69-2

Chemical Formula: C21H22N4O6

Exact Mass: 426.1539

Molecular Weight: 426.43

Elemental Analysis: C, 59.15; H, 5.20; N, 13.14; O, 22.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Wy 27569; Wy27569; Wy-27569

IUPAC/Chemical Name

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-(1H-imidazol-1-ylmethyl)-6-methyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester

InChi Key

BFLKGKGRZKABHQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H22N4O6/c1-4-31-21(27)19-16(11-24-9-8-22-12-24)23-13(2)17(20(26)30-3)18(19)14-6-5-7-15(10-14)25(28)29/h5-10,12,18,23H,4,11H2,1-3H3

SMILES Code

O=C(C1=C(CN2C=CN=C2)NC(C)=C(C(OC)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 426.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Archibald JL, Bradley G, Opalko A, Ward TJ, White JC, Ennis C, Shepperson NB. Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines. J Med Chem. 1990 Feb;33(2):646-52. PubMed PMID: 2299629. 2: Ennis C, Granger SE, Middlefell VC, Philpot ME, Shepperson NB. Pharmacologic effects of Wy 27569: a combined calcium channel blocker and thromboxane synthetase inhibitor. J Cardiovasc Pharmacol. 1989 Apr;13(4):511-9. PubMed PMID: 2470986.