MedKoo Cat#: 558945 | Name: FAM Phosphoramidite, 6-isomer
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Standard fluorescein (FAM) phosphoramidite for 5'-terminal oligonucleotide labeling, high isomeric purity single isomer. This highly purified amidite reagent ensures excellent coupling results with various synthesizers.

Chemical Structure

FAM Phosphoramidite, 6-isomer
FAM Phosphoramidite, 6-isomer
CAS#204697-37-0

Theoretical Analysis

MedKoo Cat#: 558945

Name: FAM Phosphoramidite, 6-isomer

CAS#: 204697-37-0

Chemical Formula: C46H58N3O10P

Exact Mass: 843.3860

Molecular Weight: 843.95

Elemental Analysis: C, 65.47; H, 6.93; N, 4.98; O, 18.96; P, 3.67

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
2g USD 850.00 2 Weeks
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Related CAS #
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Synonym
FAM Phosphoramidite, 6-isomer; FAM Phosphoramidite 6-isomer; 6-Fluorescein Phosphoramidite; 6-fam phosphoramidite; 5'-6-FAM-PhosphoraMidite
IUPAC/Chemical Name
6-((6-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)hexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChi Key
MGPYJVWEJNTXLC-UHFFFAOYSA-N
InChi Code
InChI=1S/C46H58N3O10P/c1-29(2)49(30(3)4)60(55-25-15-22-47)54-24-14-12-11-13-23-48-40(50)31-16-19-34-37(26-31)46(59-41(34)51)35-20-17-32(56-42(52)44(5,6)7)27-38(35)58-39-28-33(18-21-36(39)46)57-43(53)45(8,9)10/h16-21,26-30H,11-15,23-25H2,1-10H3,(H,48,50)
SMILES Code
O=C(O1)C2=CC=C(C(NCCCCCCOP(OCCC#N)N(C(C)C)C(C)C)=O)C=C2C31C4=CC=C(OC(C(C)(C)C)=O)C=C4OC5=C3C=CC(OC(C(C)(C)C)=O)=C5
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 843.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhou, Z.; Liu, S.; Zhang, Y.; Yang, X.; Ma, Y.; Guan, Z.; Wu, Y.; Zhang, L.; Yang, Z. Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells. International Journal of Nanomedicine, 2017, 12, 7255–7272. doi: 10.2147/ijn.S136726