Aminolink phosphoramidite for oligonucleotide synthesis. DMS(O)MT is a special protective group similar to traditional MMT, but designed as an improved alternative to it. DMS(O)MT aminolink is fully compatible with standard coupling, deblock, and purification protocols. However, DMS(O)MT group is much better suited for DMT-on and cartridge purification of amino-oligonucleotides because of higher stability, and better oligonucleotide recovery. Oligonucleotides containing DMS(O)MT are more stable in solution than MMT analogs.
MT aminolink C60332.jpg "DMS(O)MT aminolink C6")
MedKoo Cat#: 558944
Name: DMS(O)MT aminolink C6
CAS#: 1173109-53-9
Chemical Formula: C37H52N3O5PS
Exact Mass: 681.3365
Molecular Weight: 681.87
Elemental Analysis: C, 65.17; H, 7.69; N, 6.16; O, 11.73; P, 4.54; S, 4.70
The following data is based on the product molecular weight 681.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
 trifluoroacetate salt2259.jpg "GLP-1 (7-15) trifluoroacetate salt")