STAT5a-IN-27 is a novel cell-permeable selective STAT5a inhibitor prodrug, inhibiting tyrosine phosphorylation of STAT5a with selectivity over STAT5b in cultured human leukemia cells, and representing a valuable tool to define the non-redundant molecular functions of the two highly homologous transcription factors in tumor cells. This product was reported in Chem. Eur. J. 2020, 26, 148 – 154 (compound 27).
MedKoo Cat#: 533399
Name: STAT5a-IN-27
CAS#: N/A
Chemical Formula: C37H50FO13P
Exact Mass: 752.2973
Molecular Weight: 752.77
Elemental Analysis: C, 59.04; H, 6.70; F, 2.52; O, 27.63; P, 4.11
The following data is based on the product molecular weight 752.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
