MedKoo Cat#: 574233 | Name: (±)-Ketoprofen glucuronide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen. It is formed via glucuronidation by the UDP-glucuronosyltrasferase (UGT) isoforms UGT1A3, UGT1A9, UGT1A10, and UGT2B7.

Chemical Structure

(±)-Ketoprofen glucuronide
(±)-Ketoprofen glucuronide
CAS#76690-94-3 (glucuronide)

Theoretical Analysis

MedKoo Cat#: 574233

Name: (±)-Ketoprofen glucuronide

CAS#: 76690-94-3 (glucuronide)

Chemical Formula: C22H22O9

Exact Mass: 430.1264

Molecular Weight: 430.41

Elemental Analysis: C, 61.39; H, 5.15; O, 33.45

Price and Availability

Size Price Availability Quantity
1mg USD 650.00 2 Weeks
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Synonym
(±)-Ketoprofen glucuronide, (R,S)-Ketoprofen Glucuronide, rac-Ketoprofen Acyl-β-D-glucuronide
IUPAC/Chemical Name
(2S,3S,4S,5R,6S)-6-((2-(3-benzoylphenyl)propanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChi Key
PBTXSZZKPHBHMA-LYFYOZKASA-N
InChi Code
InChI=1S/C22H22O9/c1-11(13-8-5-9-14(10-13)15(23)12-6-3-2-4-7-12)21(29)31-22-18(26)16(24)17(25)19(30-22)20(27)28/h2-11,16-19,22,24-26H,1H3,(H,27,28)/t11?,16-,17-,18+,19-,22-/m0/s1
SMILES Code
O=C(C1=CC=CC(C(C)C(O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)=O)=C1)C3=CC=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 430.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Sabolovic, N., Heydel, J.-M., Li, X., et al. Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract. Biochim. Biophys. Acta. 1675(1-3), 120-129 (2004).