MedKoo Cat#: 558940 | Name: Alkyne Amidite, hydroxyprolinol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phosphoramidite for the synthesis of alkyne-modified oligonucleotides. Oligonucleotides can be used for Click Chemistry modification (see the protocol). Diluent for this amidite is acetonitrile, 5 min coupling time is recommended. Standard deprotection conditions can be used for oligonucleotides.

Chemical Structure

Alkyne Amidite, hydroxyprolinol
CAS#1357289-02-1

Theoretical Analysis

MedKoo Cat#: 558940

Name: Alkyne Amidite, hydroxyprolinol

CAS#: 1357289-02-1

Chemical Formula: C41H52N3O6P

Exact Mass: 713.3594

Molecular Weight: 713.85

Elemental Analysis: C, 68.98; H, 7.34; N, 5.89; O, 13.45; P, 4.34

Price and Availability

Size Price Availability Quantity
250mg USD 350.00 2 Weeks
1g USD 850.00 2 Weeks
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Related CAS #
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Synonym
IUPAC/Chemical Name
(3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(hex-5-ynoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChi Key
PLYFRZOJOFDXKE-PAGMWIRJSA-N
InChi Code
InChI=1S/C41H52N3O6P/c1-8-9-11-17-40(45)43-29-39(50-51(49-27-14-26-42)44(31(2)3)32(4)5)28-36(43)30-48-41(33-15-12-10-13-16-33,34-18-22-37(46-6)23-19-34)35-20-24-38(47-7)25-21-35/h1,10,12-13,15-16,18-25,31-32,36,39H,9,11,14,17,27-30H2,2-7H3/t36-,39+,51?/m0/s1
SMILES Code
O=C(CCCC#C)N1C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)C[C@H]1COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4
Appearance
Colorless semisolid
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 713.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL