IUPAC/Chemical Name
6-methoxy-1-(3-sulfopropyl)-quinolinium, inner salt
InChi Key
ZVDGOJFPFMINBM-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H15NO4S/c1-18-12-5-6-13-11(10-12)4-2-7-14(13)8-3-9-19(15,16)17/h2,4-7,10H,3,8-9H2,1H3
SMILES Code
COC1=CC(C=CC=[N+]2CCCS([O-])(=O)=O)=C2C=C1
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO and water
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.
Biological target:
SPQ is a fluorescent chloride indicator.
|
Solvent |
mg/mL |
mM |
comments |
| Solubility |
| DMSO |
1.0 |
3.55 |
|
| Water |
25.0 |
88.86 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
281.33
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Illsley, N.P., and Verkman, A.S. Membrane chloride transport measured using a chloride-sensitive fluorescent probe. Biochemistry 26(5), 1215-1219 (1987).
2. Soldati, L., Adamo, D., Spaventa, R., et al. Chloride fluxes activated by parathyroid hormone in human erythrocytes. Biochem. Biophys. Res. Commun. 269(2), 470-473 (2000).
3. MacVinish, L.J., Gill, D.R., Hyde, S.C., et al. Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2. J. Physiol. 499(Pt. 3), 677-687 (1997).
