MedKoo Cat#: 582090 | Name: Decyl glucoside
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Decyl glucoside synthesized by direct glucosidation of d-glucose over zeolite catalysts has estrogenicity. It is non-endocrine disruptive surfactant.

Chemical Structure

Decyl glucoside
Decyl glucoside
CAS#58846-77-8

Theoretical Analysis

MedKoo Cat#: 582090

Name: Decyl glucoside

CAS#: 58846-77-8

Chemical Formula: C16H32O6

Exact Mass: 320.2200

Molecular Weight: 320.43

Elemental Analysis: C, 59.98; H, 10.07; O, 29.96

Price and Availability

Size Price Availability Quantity
1g USD 300.00 2 Weeks
5g USD 850.00 2 Weeks
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Related CAS #
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Synonym
Decyl glucoside; Decyl beta-D-glucoside; beta-D-Glucopyranoside, decyl; Decyl beta-D-glucopyranoside; n-Decyl glucoside;
IUPAC/Chemical Name
(2R,3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
JDRSMPFHFNXQRB-IBEHDNSVSA-N
InChi Code
InChI=1S/C16H32O6/c1-2-3-4-5-6-7-8-9-10-21-16-15(20)14(19)13(18)12(11-17)22-16/h12-20H,2-11H2,1H3/t12-,13-,14+,15-,16-/m1/s1
SMILES Code
O1[C@H]([C@@H]([C@@H](O)[C@@H]([C@H]1CO)O)O)OCCCCCCCCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bai H, Tam I, Yu J. Contact Allergens in Top-Selling Textile-care Products. Dermatitis. 2020 Jan 3. doi: 10.1097/DER.0000000000000566. [Epub ahead of print] PubMed PMID: 31905182. 2: Monteiro AF, Paulino M, Máquina A, Amaro C, Viana I. Allergic contact dermatitis to decyl glucoside: Still an important allergen in Tinosorb M. Contact Dermatitis. 2019 Sep 30. doi: 10.1111/cod.13408. [Epub ahead of print] PubMed PMID: 31566773. 3: Bhoyrul B, Solman L, Kirk S, Orton D, Wilkinson M. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact Dermatitis. 2019 May;80(5):286-290. doi: 10.1111/cod.13186. Epub 2018 Dec 21. PubMed PMID: 30460735. 4: Chung KH, Kim H, Park YK, Kim BH, Kim SJ, Jung SC. Decyl Glucoside Synthesized by Direct Glucosidation of D-Glucose Over Zeolite Catalysts and Its Estrogenicity as Non-Endocrine Disruptive Surfactant. J Nanosci Nanotechnol. 2019 Feb 1;19(2):1172-1175. doi: 10.1166/jnn.2019.15900. PubMed PMID: 30360227. 5: Lasoń E, Sikora E, Miastkowska M, Escribano E, Garcia-Celma MJ, Solans C, Llinas M, Ogonowski J. NLCs as a potential carrier system for transdermal delivery of forskolin. Acta Biochim Pol. 2018;65(3):437-442. doi: 10.18388/abp.2018_2554. Epub 2018 Sep 15. PubMed PMID: 30212592. 6: Kerre S, Strobbe T, Naessens T, Theunis M, Foubert K, Aerts O. Alkyl glucosides: Newly identified allergens in foam wound dressings. Contact Dermatitis. 2018 Sep;79(3):191-193. doi: 10.1111/cod.13026. Epub 2018 May 17. Erratum in: Contact Dermatitis. 2019 Jan;80(1):76. PubMed PMID: 29774553. 7: Pajić NZB, Todosijević MN, Vuleta GM, Cekić ND, Dobričić VD, Vučen SR, Čalija BR, Lukić MŽ, Ilić TM, Savić SD. Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance. Acta Pharm. 2017 Dec 20;67(4):415-439. doi: 10.1515/acph-2017-0036. PubMed PMID: 29337676. 8: Jaque A, DeKoven JG. Polyhexamethylene biguanide and alkyl glucosides: unexpected allergens in an antimicrobial foam dressing. Contact Dermatitis. 2017 Dec;77(6):421-422. doi: 10.1111/cod.12852. PubMed PMID: 29164688. 9: Severin RK, Belsito DV. Patch Testing with Decyl and Lauryl Glucoside: How Well Does One Screen for Contact Allergic Reactions to the Other? Dermatitis. 2017 Nov/Dec;28(6):342-345. doi: 10.1097/DER.0000000000000327. PubMed PMID: 29064883. 10: Miastkowska MA, Banach M, Pulit-Prociak J, Sikora ES, Głogowska A, Zielina M. Statistical Analysis of Optimal Ultrasound Emulsification Parameters in Thistle-Oil Nanoemulsions. J Surfactants Deterg. 2017;20(1):233-246. doi: 10.1007/s11743-016-1887-7. Epub 2016 Oct 6. PubMed PMID: 28111519; PubMed Central PMCID: PMC5222920. 11: Loranger C, Alfalah M, Ferrier Le Bouedec MC, Sasseville D. Alkyl Glucosides in Contact Dermatitis. Dermatitis. 2017 Jan/Feb;28(1):5-13. doi: 10.1097/DER.0000000000000240. PubMed PMID: 27775979. 12: Grey KR, Hanson JL, Hagen SL, Hylwa SA, Warshaw EM. Epidemiology and Co-Reactivity of Novel Surfactant Allergens: A Double-Blind Randomized Controlled Study. Dermatitis. 2016 Nov/Dec;27(6):348-354. PubMed PMID: 27775977. 13: Alfalah M, Loranger C, Sasseville D. Alkyl Glucosides. Dermatitis. 2017 Jan/Feb;28(1):3-4. doi: 10.1097/DER.0000000000000234. PubMed PMID: 27775973. 14: Duangjit S, Chairat W, Opanasopit P, Rojanarata T, Panomsuk S, Ngawhirunpat T. Development, Characterization and Skin Interaction of Capsaicin-Loaded Microemulsion-Based Nonionic Surfactant. Biol Pharm Bull. 2016;39(4):601-10. doi: 10.1248/bpb.b15-00961. PubMed PMID: 27040633. 15: Abd E, Roberts MS, Grice JE. A Comparison of the Penetration and Permeation of Caffeine into and through Human Epidermis after Application in Various Vesicle Formulations. Skin Pharmacol Physiol. 2016;29(1):24-30. doi: 10.1159/000441040. Epub 2015 Nov 6. PubMed PMID: 26540487. 16: Foti C, Romita P, Rigano L, Zimerson E, Sicilia M, Ballini A, Ghizzoni O, Antelmi A, Angelini G, Bonamonte D, Bruze M. Isobornyl acrylate: an impurity in alkyl glucosides. Cutan Ocul Toxicol. 2016;35(2):115-9. doi: 10.3109/15569527.2015.1055495. Epub 2015 Jun 22. PubMed PMID: 26095233. 17: Liuti F, Borrego L. Contact dermatitis caused by Tinosorb® M: the importance of pach testing with pure methylene bis-benzotriazolyl tetramethylbutylphenol. Contact Dermatitis. 2015 Sep;73(3):192-3. doi: 10.1111/cod.12417. Epub 2015 May 11. PubMed PMID: 25962512. 18: Aerts O, Clinck B, Schramme M, Lambert J. Contact allergy caused by Tinosorb® M: let us not forget about xanthan gum. Contact Dermatitis. 2015 Feb;72(2):121-3. doi: 10.1111/cod.12324. Epub 2014 Dec 18. PubMed PMID: 25524215. 19: de Groot AC, van Zuuren EJ, Hissink D. Contact allergy to Tinosorb® M: recommendations for diagnostic improvement. Contact Dermatitis. 2014 Apr;70(4):251-4. doi: 10.1111/cod.12159. PubMed PMID: 24628353. 20: Gijbels D, Timmermans A, Serrano P, Verreycken E, Goossens A. Allergic contact dermatitis caused by alkyl glucosides. Contact Dermatitis. 2014 Mar;70(3):175-82. doi: 10.1111/cod.12154. PubMed PMID: 24588370.