Pam2Cys is a novel TLR2 agonist as potential adjuvant for cancer vaccines. Pam2Cys is a synthetic lipopeptide that mimics bacterial lipoproteins and is often used in immunological research. Here's a bit more detail: It has two palmitic acid chains and is part of the Toll-like receptor (TLR) ligand family. Pam2Cys primarily activates TLR2/6 heterodimers on immune cells, leading to the production of pro-inflammatory cytokines. This makes it a potent tool for studying innate immunity, vaccine adjuvants, and inflammatory signaling pathways. Pam2Cys enhances immune responses to co-administered antigen.
MedKoo Cat#: 533329
Name: Pam2Cys free base
CAS#: 656831-18-4 (free base)
Chemical Formula: C38H73NO6S
Exact Mass: 671.5159
Molecular Weight: 672.06
Elemental Analysis: C, 67.91; H, 10.95; N, 2.08; O, 14.28; S, 4.77
The following data is based on the product molecular weight 672.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
