Synonym
Cyanine7.5 amine; Cyanine 7.5 amine; Cyanine-7.5 amine; Cyanine7.5-amine; Cy7.5 amine; Cy 7.5 amine; Cy7.5-amine;
IUPAC/Chemical Name
3-(6-((6-ammoniohexyl)amino)-6-oxohexyl)-1,1-dimethyl-2-((E)-2-((E)-3-((E)-2-(1,1,3-trimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)cyclohex-1-en-1-yl)vinyl)-1H-benzo[e]indol-3-ium chloride
InChi Key
VVNSSDUAJNZJAL-UHFFFAOYSA-N
InChi Code
InChI=1S/C51H62N4O.2ClH/c1-50(2)45(54(5)43-29-27-39-20-10-12-22-41(39)48(43)50)31-25-37-18-17-19-38(36-37)26-32-46-51(3,4)49-42-23-13-11-21-40(42)28-30-44(49)55(46)35-16-8-9-24-47(56)53-34-15-7-6-14-33-52;;/h10-13,20-23,25-32,36H,6-9,14-19,24,33-35,52H2,1-5H3;2*1H
SMILES Code
CN1/C(C(C)(C)C2=C1C=CC3=CC=CC=C23)=C/C=C4C=C(/C=C/C5=[N+](CCCCCC(NCCCCCC[NH3+])=O)C6=C(C7=CC=CC=C7C=C6)C5(C)C)CCC/4.[Cl-].[Cl-]
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
820.00
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
2. Melo, M.; Nunes, R.; Sarmento, B.; das Neves, J. Colorectal distribution and retention of polymeric nanoparticles following incorporation into a thermosensitive enema. Biomaterials Science, 2019, 7(9), 3801–3811. doi: 10.1039/c9bm00759h
3. Hauser-Kawaguchi, A.; Milne, M.; Li, F.; Lee, T.Y.; Luyt, L.G. The development of a near infrared inulin optical probe for measuring glomerular filtration rate. International Journal of Biological Macromolecules, 2019, 123, 255–260. doi: 10.1016/j.ijbiomac.2018.11.034
4. Li, Y.; Xiao, Y.; Lin, H.-P.; Reichel, D.; Bae, Y.; Lee, E.Y.; Jiang, Y.; Huang, X.; Yang, C.; Wang, Z. In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis. Biomaterials, 2019, 188, 160–172. doi: 10.1016/j.biomaterials.2018.10.019