Suramin free acid | CAS#129-46-4

MedKoo Cat#: 533269 | Name: Suramin free acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Suramin hexasodium salt is a topoisomerase II inhibitor, blocking the binding of the enzyme to DNA inhibiting FGFa, FGFb, and PGDF, uncoupling G-proteins from receptors, and antagonizing P2X and P2Y purinergic receptors.

Chemical Structure

Suramin free acid

CAS#145-63-1 (free acid)

Theoretical Analysis

MedKoo Cat#: 533269

Name: Suramin free acid

CAS#: 145-63-1 (free acid)

Chemical Formula: C51H40N6O23S6

Exact Mass: 1296.0469

Molecular Weight: 1297.26

Elemental Analysis: C, 47.22; H, 3.11; N, 6.48; O, 28.37; S, 14.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

145-63-1 (free acid) 129-46-4 (sodium)

Synonym

Suramin hexasodium salt

IUPAC/Chemical Name

8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonic acid)

InChi Key

FIAFUQMPZJWCLV-UHFFFAOYSA-N

InChi Code

InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)

SMILES Code

O=S(C1=C2C(NC(C3=CC=C(C(NC(C4=CC=CC(NC(NC5=CC=CC(C(NC6=CC(C(NC7=C8C(S(=O)(O)=O)=CC(S(=O)(O)=O)=CC8=C(C=C7)S(=O)(O)=O)=O)=CC=C6C)=O)=C5)=O)=C4)=O)=C3)C)=O)=CC=C(C2=CC(S(=O)(O)=O)=C1)S(=O)(O)=O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 1,297.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.