MedKoo Cat#: 582060 | Name: Declenperone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Declenperon acts as a reagent for antimalarial drug lead identification. The are also used in the chemical development of selective and specific serotonin S2-antagonists.

Chemical Structure

Declenperone
Declenperone
CAS#63388-37-4

Theoretical Analysis

MedKoo Cat#: 582060

Name: Declenperone

CAS#: 63388-37-4

Chemical Formula: C22H24FN3O2

Exact Mass: 381.1900

Molecular Weight: 381.45

Elemental Analysis: C, 69.27; H, 6.34; F, 4.98; N, 11.02; O, 8.39

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Synonym
Declenperone; Declenperona; Declenperonum; R 33,204; R 33204; UNII-280VGV0X4H.
IUPAC/Chemical Name
2H-Benzimidazol-2-one, 1-(3-(4-(4-fluorobenzoyl)-1-piperidinyl)propyl)-1,3-dihydro-
InChi Key
VNLMLHDKNUIWNM-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H24FN3O2/c23-18-8-6-16(7-9-18)21(27)17-10-14-25(15-11-17)12-3-13-26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-9,17H,3,10-15H2,(H,24,28)
SMILES Code
O=C1NC2=CC=CC=C2N1CCCN3CCC(C(C4=CC=C(F)C=C4)=O)CC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Declenperon acts as a reagent for antimalarial drug lead identification .
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 381.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD