MedKoo Cat#: 558831 | Name: Cyanine5.5 maleimide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide. Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications. Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.

Chemical Structure

Cyanine5.5 maleimide
Cyanine5.5 maleimide
CAS#1593644-50-8 (PF6)

Theoretical Analysis

MedKoo Cat#: 558831

Name: Cyanine5.5 maleimide

CAS#: 1593644-50-8 (PF6)

Chemical Formula: C46H49F6N4O3P

Exact Mass: 0.0000

Molecular Weight: 850.89

Elemental Analysis: C, 64.93; H, 5.80; F, 13.40; N, 6.58; O, 5.64; P, 3.64

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 650.00 2 Weeks
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Related CAS #
Synonym
Cyanine5.5 maleimide; Cyanine 5.5 maleimide; Cy5.5 maleimide; Cy 5.5 maleimide; Cy5.5-maleimide;
IUPAC/Chemical Name
2-((1E,3E,5E)-5-(3-(6-((2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium hexafluorophosphate
InChi Key
OGNRSSLDSDZMBZ-UHFFFAOYSA-O
InChi Code
InChI=1S/C46H48N4O3.F6P/c1-45(2)38(48(5)36-25-23-32-16-11-13-18-34(32)43(36)45)20-8-6-9-21-39-46(3,4)44-35-19-14-12-17-33(35)24-26-37(44)49(39)30-15-7-10-22-40(51)47-29-31-50-41(52)27-28-42(50)53;1-7(2,3,4,5)6/h6,8-9,11-14,16-21,23-28H,7,10,15,22,29-31H2,1-5H3;/q;-1/p+1
SMILES Code
C[N+]1=C(/C=C/C=C/C=C2N(CCCCCC(NCCN3C(C=CC3=O)=O)=O)C4=C(C5=CC=CC=C5C=C4)C/2(C)C)C(C)(C)C6=C1C=CC7=CC=CC=C67.F[P-](F)(F)(F)(F)F
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 850.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508 2. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905 3. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383 4. Guo, S.; Xiao, X.; Wang, X.; Luo, Q.; Zhu, H.; Zhang, H.; Li, H.; Gong, Q.; Luo, K. Reductive microenvironment responsive gadolinium-based polymers as potential safe MRI contrast agents. Biomaterials Science, 2019, 7(5), 1919–1932. doi: 10.1039/c8bm01103f