MedKoo Cat#: 465035 | Name: BSJ-04-132
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BSJ-04-132 shows dose-dependent degradation of CDK4 with maximum degradation at 0.5uM in Jurkat cells.

Chemical Structure

BSJ-04-132
BSJ-04-132
CAS#2349356-39-2

Theoretical Analysis

MedKoo Cat#: 465035

Name: BSJ-04-132

CAS#: 2349356-39-2

Chemical Formula: C42H49N11O7

Exact Mass: 819.3816

Molecular Weight: 819.92

Elemental Analysis: C, 61.53; H, 6.02; N, 18.79; O, 13.66

Price and Availability

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5mg USD 650.00 2 Weeks
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Related CAS #
2349356-39-2;
Synonym
BSJ-04-132; BSJ04132; BSJ 04 132;
IUPAC/Chemical Name
7-cyclopentyl-2-((5-(4-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
InChi Key
GWLSXEHHNOBFOI-UHFFFAOYSA-N
InChi Code
InChI=1S/C42H49N11O7/c1-49(2)40(58)31-22-26-23-45-42(48-37(26)52(31)27-8-3-4-9-27)46-33-14-12-28(24-44-33)51-20-18-50(19-21-51)17-6-5-16-43-35(55)25-60-32-11-7-10-29-36(32)41(59)53(39(29)57)30-13-15-34(54)47-38(30)56/h7,10-12,14,22-24,27,30H,3-6,8-9,13,15-21,25H2,1-2H3,(H,43,55)(H,47,54,56)(H,44,45,46,48)
SMILES Code
CN(C)C(=O)C1=CC2=CN=C(NC3=CC=C(C=N3)N3CCN(CCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)N=C2N1C1CCCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 819.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Angew. Chem. Int. Edit., 2019, 58, 6321-6326. (https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201901336) 2. https://graylab.dana-farber.org/probes.html